8923 - Vortioxetine

Material & Volume
  • Serum, 1ml
Reference values
Age Sex Pregnant Range Unit
All No 10-40 therapeutic range
>80 toxic
µg/l
Clinical Information

Vortioxetin is an anti-depressive agent of the ‘SARI‘ Group of serotonin antagonists and re-uptake inhibitors. This medication is administered for cases of major depression, whereby the broad spectrum of depressive syndromes is therapized. The agent is a serotonin modulator and stimulator and inhibits the re-uptake of serotonin, and thus enhances the concentration of the neuro-transmitter in the central nervous system. The active ingredient becomes bound to a variety of serotonin receptors, as being a partial agonist and antagonist in itself. This has effects on various other neuro-transmitter systems. Frequent side effects are nausea, vomiting, diarrhoea and itching of the skin.

Type of drug: Antidepressant
Metabolism: CYP2D6, CYP3A4, CYP2A6, CYP2C9, P-gp(ABCB1)
Half life t½: 57-66h
Steady State: 2 weeks
TDM: recommended
Additional informations: At least 4 inactive metabolites

More information
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  • Brintellix®
Position / Price
Position: 1065.00
Price: CHF 126.00
+ Processing fee:
(per order and per day)
CHF 21.60
Method
  • LC-MS
Executing laboratory
labor team w ag
Blumeneggstrasse 55
9403 Goldach
Execution time
1 day
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